Buffalo & Amherst: 716.881.7900

Orchard Park: 716.677.6500

Buffalo & Amherst: 716.881.7900
Orchard Park: 716.677.6500
Josh J. Wang, MD, MS - Vision Research Center

Josh J. Wang, MD, MS

Vision Research Center

1176 Main St.
Buffalo, NY 14209
Phone: 716-645-1807
Email: jianxinw@buffalo.edu

Title and Department:
Associate Professor of Research
Ophthalmology and Internal Medicine

Education and Training:
M.D. Yunyang Medical College, Tongji University of Medical Sciences, Hubei, China
M.S. (Medicine-Cardiology) Sun Yat-sen University of Medical Sciences, Guangzhou, China

Clinical Fellowship (Cardiology):
The First People’s Hospital of Guangzhou, Guangzhou, China

Residency (Internal Medicine):
Yunyang Medical College-University Hospital, Tongji University of Medical Sciences, Hubei, China

Medical University of South Carolina, Charleston, SC (Ophthalmology/Molecular Biology)

University of Oklahoma Health Sciences Center, Oklahoma City, OK (Medicine/Cell Biology)

Research Focus:

Collaborative clinical and epidemiological research/clinical trials, fundamental retinal processes, retinal diseases

Clinical Relevance:

Age-related macular degeneration, diabetic retinopathy, vascular diseases

Synopsis of Research:

Dr. Josh J. Wang, M.D., M.S. focuses his research on studying diabetic-related vascular complications, including diabetic retinopathy, diabetic vascular disease, insulin resistance and diabetic nephropathy. In addition to addressing mechanisms, our cellular and biochemical studies are meant to develop cures for diseases that affect the retina, peripheral vessel and kidney.

1. Diabetic retinopathy: Focusing on endoplasmic reticulum (ER) stress activation and interactions among ER stress, oxidative stress and inflammation in retina.

2. Periphral vascular disease (PVD): Endothelial cells in the vascular system are especially vulnerable to hyperglycemic conditions. Exploring endothelial dysfunction in diabetic setting, would aid in the search for novel approaches in the prevention of diabetes vascular disease.

3. Diabetic nephropathy: Glomerular endothelial cells and podocytes are primary sites of injury resulting in chronic kidney disease in diabetes. We investigate the function of endogenous angiogenic inhibitors in regulation of renal cells in diabetic kidney.

4. Adipocyte and insulin resistance: Studying the function of PEDF in adipogenesis, provide pivotal information for understanding the mechanisms underlying the association of PEDF, obesity and insulin resistance.

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Buffalo Niagara
Medical Campus

1176 Main St.
Buffalo, NY 14209
P: 716-881-7900
F: 716-881-4349

Office Hours:
M-F 8a.m. - 4:30p.m.

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Northtowns Office

3580 Sheridan Drive
Suite 150
Amherst, NY 14226
P: 716-881-7900
F: 716-833-4916

Office Hours:
M-F 8a.m. - 4:30p.m.

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Southtowns Office

301 Sterling Drive
Orchard Park, NY 14127
P: 716-677-6500
F: 716-677-6507

Office Hours:
M-F 8a.m. - 4:30p.m.

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Your vision is of utmost importance to us.

At the Ross Eye Institute, we understand the importance of continuing to meet your vision care needs. We take your health and COVID-19 precautions very seriously. Your health, and ours is of utmost importance.

- We follow the Department of Health guidelines.
- Doctors and staff undergo daily screening questions as well as temperature checks twice a day.
- Access to our facility is limited to our patients only. If a patient cannot attend their appointment on their own, an escort will also be permitted.
- Patients who arrive more than 15 minutes prior to their appointment will not be allowed inside until it gets closer to their scheduled appointment time. Please plan accordingly.
- Patient and staff touch points are sanitized between each use and logs are maintained documenting strict adherence.
- Proper mask use is strictly enforced.
- We are not allowing visits from pharmaceutical reps, vendors, or other salespersons or business associates.

Your vision care is a critical component to maintaining long-term vision health and the Ross Eye Institute remains committed to meeting your vision care needs while keeping you safe, during these uncertain times.