Ongoing Clinical Research Studies
Current Research
Staff at the Ross Eye Institute and REI’s Vision Research Center are active in research to treat, reverse and even prevent vision and ocular conditions and diseases. Learn more about the ongoing clinical research studies our staff is investigating.

Association Between Fuchs’ Endothelial Corneal Dystrophy Severity and Estrogen Exposure
PI: Sangita Patel, MD, PhD
Sponsor: National Institutes of Health
Brief Summary: This study is being done to discover if there is a link between estrogen exposure and the severity of Fuchs endothelial corneal dystrophy. We are trying to understand if the decrease in estrogen levels in post-menopausal women may be a reason why Fuchs dystrophy is seen more often in women than men. We are looking for men and women over age 55 years with a diagnosis of mild or severe Fuchs dystrophy. Recruitment for this study will close in 2023.
Contact: Sharon Michalovic sab1@buffalo.edu / 716-881-7975
Binocular Dig Rush Game Treatment for Amblyopia
PI: John Lillvis, MD, PhD
Sponsor: National Eye Institute
Brief Summary: To compare the efficacy of 1 hour/day of binocular game play 5 days per week plus spectacle correction with spectacle correction only, for treatment of amblyopia in children 4 to <7 years of age. Recruitment for this study will close November 2020 or when enrollment goal is achieved.
Contact: Sharon Michalovic sab1@buffalo.edu / 716-881-7975, Samantha Pape spape@buffalo.edu
The STAAR Study
PI: Andrew Reynolds, MD
Sponsor: Sydnexis
Brief Summary: A phase III study testing an investigational eye drop to slow the progression of nearsightedness (myopia). The study is screening children ages 3-14 years of age who are nearsighted. All eligible subjects are compensated for each clinical visit. Recruitment for this study will close in April of 2020.
Contact Sharon Michalovic sab1@buffalo.edu / 716-881-7975


Buffalo Niagara
Medical Campus
1176 Main St.
Buffalo, NY 14209
P: 716-881-7900
F: 716-881-4349
Northtowns Office
3580 Sheridan Drive
Suite 150
Amherst, NY 14226
P: 716-881-7900
F: 716-833-4916